Do you really believe in hope and change?

What if you've just been screwed up for as long as you can remember, and the pills don't work enough and the therapy doesn't work enough and the prayers aren't answered and all the love and sympathy just isn't enough? And it gets worse every day and and shows no sign of change and no escape and nothing eases the pain and mental torment? What if you can't change your perspective, no matter how long and hard you try? They say it gets better for everyone and everything works out but everyone's killing themselves anyway and people drink themselves to death, and people being miserable right into their old age and death really isn't unheard of. Do you think there is hope for people who can't seem to change?